Your only source for venom extracts

As the sole venom immunotherapy provider in the United States, we take seriously our commitment to manufacturing the highest quality extracts possible. Our venom passes a minimum of 15 separate quality checks before we release it to you, and our manufacturing process for standardized venom adheres to strict quality controls.1

From Field to Vial

Multi-Phase Processing

The process of manufacturing venom extracts includes:

  1. Collecting the specific insect species
  2. Dissection and manufacturing the processed (bulk) raw material
  3. Reconstituting and filling operation for the final product
  4. Labeling and packaging

Venom Manufacturing Q&A

For all species except Honey Bee, vacuuming from hives, then freezing the insect, is the most common method.

Because of their importance as pollinators, Honey Bees are kept alive. Their venom is collected by applying a mild, harmless electrical current to a glass plate. Upon landing, the current causes the Honey Bee to sting, depositing a drop of venom on the glass.

We collect up to 14 different species.

It depends on the species, usually 40-50 insects.

Twenty-nine different steps must be completed to make a finished vial of venom.


We created the BeeAware program to inform the public and physicians about VIT life-saving treatment, demonstrating our commitment to both patients and allergists. At, patients are able to locate a physician near them for VIT treatment.

Featured Downloads

6781 – 6785 Venomil® Diagnostic Sets 2 mL Diagnostic Vials
6781 – 6786 See product catalog for available presentations Venomil® Maintenance Sets 2 mL Maintenance Vials
Multidose Hymenoptera Venom Products 5-Dose 12-Dose Multidose Vials


1 HollisterStier Allergy’s manufacturing plant is regulated by both CBER and CDER.

2 M.D. Valentine, K.C. Schuberth, A. Kagey-Sobotka, D.F. Graft, K.A. Kwiterovich, M. Szklo, et al. The Value of Immunotherapy with Venom in Children With Allergy to Insect Stings. N. Engl J. Med. 323:1601-3 (1990).

3 M.D. Valentine. Anaphylaxis and Stinging Insect Hypersensitivity. JAMA 268:2830-2833 (1992).

4 Golden et al. Stinging insect hypersensitivity: