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Venom immunotherapy keeps patients out of the ER and saves lives.

Hymenoptera venom allergy is one of the most common causes of anaphylaxis in adults. In fact, roughly 7% of the United States population is at risk for a severe reaction with their next bee or wasp sting.3 Because of their allergy, 220,000 people will visit the emergency room next year, unless they are treated by an allergist.4

Proven Effectiveness.2 Unsurpassed Standards.

Venom Immunotherapy (VIT) reduces the risk of systemic reaction for patients allergic to stinging insects — with an efficacy rating of up to 98%.2

Our high-quality hymenoptera venom passes a minimum of 12 separate quality checks before we release it to you.1 From raw material processing to the final container, one lot of yellow jacket finished product takes approximately 300 hours to complete.

6781 – 6786 Multidose Hymenoptera Venom Products See product catalog for available presentations

BeeAware Allergy

BeeAware Allergy is a patient education campaign operated by HollisterStier Allergy. It is a product of our committment to increasing awareness of bee sting allergies and venom immunotherapy. That way, physicians can focus on what matters most: treating patients.

At, those with allergy concerns are directed to use the physician locator. Its a tool for easily discovering local VIT providers. Medical professionals who visit the website are encouraged to share information about VIT with their patients. To assist, BeeAware will ship printed education materials for medical professionals to distribute, completely free. Lastly, BeeAware offers a social media toolkit. Anyone is free to download and post the photos, videos, and statistics found there.

Download or Request Patient Education Matierals

Venom Manufacturing Q&A

For all species except Honey Bee, vacuuming from hives, then freezing the insect, is the most common method.

Because of their importance as pollinators, Honey Bees are kept alive. Their venom is collected by applying a mild, harmless electrical current to a glass plate. Upon landing, the current causes the Honey Bee to sting, depositing a drop of venom on the glass.

We collect up to 14 different species.

It depends on the species, usually 40-50 insects.

Twenty-nine different steps must be completed to make a finished vial of venom.

From Field to Vial

Multi-Phase Processing

The process of manufacturing venom extracts includes:

  1. Collecting the specific insect species
  2. Dissection and manufacturing the processed (bulk) raw material
  3. Reconstituting and filling operation for the final product
  4. Labeling and packaging


1 HollisterStier Allergy’s manufacturing plant is regulated by both CBER and CDER.

2 Golden, David B.K. et al. Stinging insect hypersensitivity: A practice parameter update 2016. Ann Allergy Asthma Immunol, Vol 118, 28-54.

3 Boyle, R., & Ludman, S. (2015). Stinging insect allergy: Current perspectives on venom immunotherapy. Journal of Asthma and Allergy, 75-86. doi:10.2147/jaa.s62288

4 Forrester, J. A., Weiser, T. G., & Forrester, J. D. (2018). An Update on Fatalities Due to Venomous and Nonvenomous Animals in the United States (2008–2015). Wilderness & Environmental Medicine, 29(1), 36-44. doi:10.1016/j.wem.2017.10.004