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Highest Concentrated Histamine on the Market

Insufficient histamine concentration in allergy testing can compromise accurate diagnoses and patient care.2 Therefore, it is crucial for providers to have a reliable histamine product that delivers precise results for optimal patient treatment.

Avoid potential issues by exploring the advantages of utilizing a concentrated product that delivers reliable results, empowering you to provide the highest level of care with confidence.

HollisterStier Allergy’s Histamine Positive Control 5mL Scratch is designed  to be the recommended concentration for dependable and precise results.1,2,3,4

Histamine Extract

Expert-Recommended Histamine by HollisterStier Allergy

  • Expert-Recommended Strength: Middleton’s Allergy: Principles and Practice recommends 10 mg/mL as the “preferred positive control for prick-puncture tests.”1 This is the exact concentration in our histamine positive control.
  • Recommended Strength: Skin Prick Testing and the Use of Histamine References recommends “histamine 10 mg/mL as an international positive reference.”2
  • Established Efficacy: Our histamine dihydrochloride concentration is backed by extensive scientific data, widely recognized as the European standard dating back to original Nordic guidelines.3
  • Enhanced Reliability: “Histamine Dihydrochloride at 10mg/mL (6 mg/mL histamine base) has been shown to elicit fewer false negatives and false positives” when using the same skin testing device.4

Start Using Effectively-Concentrated Histamine

Utilize HollisterStier Allergy’s Histamine Positive Control and experience long-trusted accuracy in allergy diagnosis. Your patients deserve nothing less, and you deserve the tools that deliver exceptional care.

HollisterStier Allergy's histamine

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1 N.F. Adkinson, B. B. (2014). Middleton’s Allergy: Principles and Practice. 8th ed., 1123.
2 H.J. Malling. Skin Prick Testing and the Use of Histamine References. Allergy, 39: 596-601, (1984).
3 Nordic Council on Medicines: Registration of Allergen Preparations. Nordic Guidelines, ed 1. Uppsala, NLN Publications, 1982, No 7, pp 16.
4 R.B. Berkowitz, D.G. Tinkleman, D. Lurz, et al. Evaluation of the Multi-test Device for Immediate Hypersensitivity Skin Testing. J. Allergy Clin. Immunol. 90: 979-985 (1992)