Allergy Immunotherapy

Allergy shots, also known as subcutaneous immunotherapy (SCIT), are the most commonly used and most effective form of allergy immunotherapy. SCIT is the only treatment available that actually changes the immune system, making it possible to prevent the development of new allergies and asthma.1

HollisterStier Allergy has been an innovator in the allergy market since 1921, when our company founders were searching to relieve the allergy suffering of family members. We offer high-quality products that can’t be found anywhere else and our histamine and AP Dog products are named in the Allergy practice parameters.2,3

AP Dog

This groundbreaking product has the highest concentration of dog hair extract available on the market. Studies suggest that AP Dog is more effective than other dog antigens in both the diagnosis and treatment of allergies.4,5

Learn more about AP Dog


Venom immunotherapy can be a life-saving treatment for patients with severe sensitivity to bee, wasp, or hornet venom. Whether you choose our diagnostic or maintenance sets, or our 5- and 12-dose vials, you can be sure that we understand the importance of venom immunotherapy to your patients with severe bee and wasp allergies. As the only supplier of venom extracts in the U.S. market, we continue to grow and improve our venom production capabilities.


We introduced mite extracts in 1988, and we culture our own source material to produce our mite products, including our highly concentrated 30,000 AU/mL option.

Learn more about Mite Extracts

The Phenol Free Difference

Our glycerinated extracts do not use phenol in the extraction process. Instead we use 50% glycerin in our extraction process, to avoid any potency issues or degradation of proteins. Phenol has been shown to denature proteins, including those in allergen extracts.6 The table below illustrates the denaturing effect of phenol on potency over time.7


1 American College of Allergy, Asthma & Immunology. (2014). Allergy Immunotherapy. Retrieved from:

Cox et. al. (2011). Allergen Immunotherapy: A practice parameter third update. The Journal of Allergy and Clinical Immunology.

I.L. Berstein, et al. Practice parameters for the diagnosis and treatment of asthma. Annals of Allergy Asthma Immunology. 2008; 96:S1– S148.

Turbeyville, et al. (2008). Discordance Between Conventional and Acetone Precipitate (AP) Dog Extract in Skin Prick Testing. The Journal of Allergy and Clinical Immunology, 121(2).

Lent, et al. (2006). Immunologic response to administration of standardized dog allergen extract at differing doses. The Journal of Allergy and Clinical Immunology, 118(6).

6 H.S. Nelson. (2004). Preparing and Mixing Allergen Vaccines. In Lockey et. al, Allergens and Allergen Immunotherapy (3rd ed., p. 472)

7Center, J. George et al. (1974) Table adapted from: Stability of Antigen E in commercially prepared ragweed pollen extracts. The Journal of Allergy and Clinical Immunology.