Three Questions

Allergens are present in every environment, so choosing the right allergenic extract partner isn’t just important; it’s vital for the health of your patients, and the health of your practice.

That means finding a partner just as committed as you are. We are that ideal partner, because we’re not afraid of the tough questions. So ask us, and then ask anyone else these same questions.

1. What are your product innovations and differentiations?

2. How do you ensure quality control and manufacturing standards?

3. What shows your commitment to my practice and my patients?

Three Answers

1. Innovations & Differentiations

HollisterStier has been an innovator since our founding in 1921. In fact, both our histamine and AP Dog products are listed in the Allergy practice parameters.4,5 Now approaching our 100th year, we have produced many breakthroughs.

Our exclusive process, often using as much as 50 times the source material, creates highly potent extract.

We do not use phenol in any of our glycerin extracts, which helps prevent denaturing of the proteins. This, in turn, helps preserve potency.3

Our focus has always been on subcutaneous immunotherapy and bulk extracts. We create products specifically for allergists and allergy specialists.

As a result, we are able to offer many high-quality products, such as:


The highest concentration of dog hair extract available based on major allergen content. Studies indicate it’s more effective for diagnosis and treatment.1,2


We introduced mite extracts in 1988, and culture our source material to produce mite products—including a highly concentrated bulk extract.


Our venom products pass a minimum of 15 quality control checks. We are the only supplier of venom in the U.S.


The only ten-test, self-loading, surgical steel skin test device on the market.

2. Quality Control & Manufacturing Standards

HollisterStier’s facility is rigorously inspected by CBER, CDER and multiple foreign agencies, exhibiting strong GMP standards.

We strive to meet multiple agency guidelines as part of our commitment to high-quality allergenic extracts for you and your patients. This requires careful control and exacting processes.

3. Commitment to Your Practice & Patients

Our focus, subcutaneous immunotherapy, has been shown in studies to be effective for  treatment of allergies. We continue to innovate our manufacturing methods. We’ve invested in equipment, technology and facilities. And we’ve responded to your needs and wants by creating a product portfolio that focuses on the antigens most important to you.

Finally, we are patient-focused in what we produce. We offer educational materials to help answer the questions your patients ask. For instance, we created and funded the BeeAware Program to inform the public about VIT, demonstrating our commitment to both patients and allergists.


1 J.C. Turbeyville, M. Nelson, C. Mikita. Discordance Between Conventional and Acetone Precipitated (AP) Dog Extract in Skin Prick Testing. The Journal of Allergy and Clinical Immunology, Volume 121, Issue 2 (2008).

2 Anne M. Lent, MD, Ronald Harbeck, PhD, Matthew Strand, PhD, Michael Sills, BS, Kimberly Schmidt, RN, BSN, Benjamin Efaw, MS, Terri Lebo, BS, and Harold S. Nelson, MD. Immunologic response to administration of standardized dog allergen extract at differing doses. The Journal of Allergy and Clinical Immunology, Volume 118, No. 6 (2006).

3 H.S. Nelson. Preparing and mixing allergen vaccines for subcutaneous immunotherapy. R.F. Lockey, S.C. Bukantz, & J. Bousquet (Eds.), Allergens and allergen immunotherapy, 4th ed., p. 315, 2008.

4 Cox ET AL. Allergen Immunotherapy: A practice parameter third update. The Journal of Allergy and Clinical Immunology, January 2011.

5 I.L. Berstein, et al. Practice parameters for the diagnosis and treatment of asthma. Ann Allergy Asthma Immunol. 2008; 96:S1– S148.