Histamine
Highest Concentrated Histamine on the Market
Insufficient histamine concentration in allergy testing can compromise accurate diagnoses and patient care.2 Therefore, it is crucial for providers to have a reliable histamine product that delivers precise results for optimal patient treatment.
Avoid potential issues by exploring the advantages of utilizing a concentrated product that delivers reliable results, empowering you to provide the highest level of care with confidence.
HollisterStier Allergy’s Histamine Positive Control 5mL Scratch is designed to be the recommended concentration for dependable and precise results.1,2,3,4
Expert-Recommended Histamine by HollisterStier Allergy
- Expert-Recommended Strength: Middleton’s Allergy: Principles and Practice recommends 10 mg/mL as the “preferred positive control for prick-puncture tests.”1 This is the exact concentration in our histamine positive control.
- Recommended Strength: Skin Prick Testing and the Use of Histamine References recommends “histamine 10 mg/mL as an international positive reference.”2
- Established Efficacy: Our histamine dihydrochloride concentration is backed by extensive scientific data, widely recognized as the European standard dating back to original Nordic guidelines.3
- Enhanced Reliability: “Histamine Dihydrochloride at 10mg/mL (6 mg/mL histamine base) has been shown to elicit fewer false negatives and false positives” when using the same skin testing device.4
Intended for use only by licensed health care provider experienced in administering allergenic extracts and trained to provide immediate emergency treatment in the event of a life-threatening reaction. Observe patients for at least 30 minutes following administration. Immunotherapy may not be suitable for patients with medical conditions that reduce their ability to withstand a systemic reaction. Allergenic extracts can cause serious systemic reactions, including anaphylactic shock and in rare cases death, especially in patients who have severe or steroid dependent asthma, cardiovascular disease, or in patients who use beta blockers. Do not inject intravenously. This product is intended for subcutaneous injection for immunotherapy and percutaneous use for diagnosis. Refer to contraindications, warnings, precautions, adverse reaction and over dosage for more detailed information.
Start Using Effectively-Concentrated Histamine
Utilize HollisterStier Allergy’s Histamine Positive Control and experience long-trusted accuracy in allergy diagnosis. Your patients deserve nothing less, and you deserve the tools that deliver exceptional care.
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1 N.F. Adkinson, B. B. (2014). Middleton’s Allergy: Principles and Practice. 8th ed., 1123.
2 H.J. Malling. Skin Prick Testing and the Use of Histamine References. Allergy, 39: 596-601, (1984).
3 Nordic Council on Medicines: Registration of Allergen Preparations. Nordic Guidelines, ed 1. Uppsala, NLN Publications, 1982, No 7, pp 16.
4 R.B. Berkowitz, D.G. Tinkleman, D. Lurz, et al. Evaluation of the Multi-test Device for Immediate Hypersensitivity Skin Testing. J. Allergy Clin. Immunol. 90: 979-985 (1992)





